Dr. Brufsky on Trastuzumab Biosimilars in Breast Cancer

Adam M. Brufsky, MD, PhD, professor of medicine, associate chief, Division of Hematology/Oncology, co-director, Comprehensive Breast Cancer Center, associate director, Clinical Investigation, University of Pittsburgh Medical Center Hillman Cancer Center, discusses the utility of trastuzumab (Herceptin) biosimilars in breast cancer.

Currently, 5 trastuzumab biosimilars have been approved by the FDA for use in HER2-positive breast cancer.

There may be subtle differences among the individual agents; however, the drugs should be considered the same, says Brufsky.

Selecting the optimal agent will ultimately come down to availability and cost rather than medical factors, he concludes.