Gynecologic Oncology Articles

Adjuvant Chemotherapy Reduces Distant Recurrence Risk in Cervical Cancer
Systemic chemotherapy administered post-surgery reduced the risk for distant recurrence in women with node-positive stage IB-IIB cervical cancer.
Nivolumab Active in Advanced Gynecologic Cancers
Nivolumab demonstrated clinical activity in women with recurrent/metastatic cervical cancer, and was active to a lesser extent in vaginal and vulvar cancers.
ODAC Unanimously Supports Bevacizumab Biosimilar ABP-215
The FDA’s Oncologic Drugs Advisory Committee voted 17-0 to recommend approval for ABP-215, a biosimilar for bevacizumab (Avastin) to treat a range of solid tumors.
Expert Discusses Recent Endometrial Cancer Research
Rebecca C. Arend, MD, discusses highlights from the ASCO meeting and other key developments in endometrial cancer.
Lurbinectedin Shows Promise in Endometrial Cancer
Lurbinectedin (PM01183) induced a high rate of response as monotherapy and with doxorubicin or paclitaxel in patients with advanced endometrial cancer.
Pembrolizumab Demonstrates Durable Response in PD-L1+ Endometrial Cancer
Results from the KEYNOTE-028 study showed that pembrolizumab (Keytruda) was associated with a median duration of response of 6 months and a 6-month progression-free survival rate of 40.4% in women with advanced PD-L1–positive endometrial cancer.
Study Warns Women of Premature Discontinuation of Cervical Cancer Screening
Mary C. White, ScD, MPH, discusses the unmet needs near and after the stopping age for cervical cancer screening.
Zoptarelin Doxorubicin Falls Short in Phase III Endometrial Cancer Trial
Zoptarelin doxorubicin (Zoptrex), a hybrid molecule combining an LHRH-agonist and doxorubicin, failed to improve median overall survival in a phase III advanced endometrial cancer trial, according to the manufacturer of the treatment, Aeterna Zentaris.
Bariatric Surgery Associated With Reduced Risk for Female-specific Cancers
Women who underwent bariatric surgery to combat obesity were less likely to develop any cancer and female-specific cancers, as demonstrated in results published in Gynecologic Oncology.
Expert Addresses Issues in Advanced Gynecologic Cancers
Dana Chase, MD, discusses obstacles to progress and her hope for the future in advanced gynecologic cancers.
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