Dr. Haas on Adjuvant Sorafenib or Sunitinib for RCC

Video

Naomi B. Haas, MD, associate professor, Abramson Cancer Center of the University of Pennsylvania, discusses the phase III ASSURE trial which looks at sorafenib or sunitinib for locally advanced renal cell carcinoma (RCC).

Naomi B. Haas, MD, associate professor, Abramson Cancer Center of the University of Pennsylvania, discusses the phase III ASSURE trial which looks at sorafenib or sunitinib for locally advanced renal cell carcinoma (RCC).

It was hypothesized that sorafenib or sunitinib could extend disease-free survival in the adjuvant setting. To test this, patients were classified based on risk (intermediate-high or very high), clear or non-clear histology, ECOG performance status, and surgery approach and treated for a year with either sunitinib, sorafenib, or placebo.

It was found that neither sorafenib nor sunitinib improved outcomes when administered after surgery to patients with RCC.

<<<

View more from the 2015 GU Cancer Symposium

Related Videos
Jaime R. Merchán, MD, professor, co-leader, Translational and Clinical Oncology Research Program, director, Phase 1 Clinical Trials Program, Department of Medicine, Division of Medical Oncology, the University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center
Wenxin (Vincent) Xu, MD,
Wenxin (Vincent) Xu, MD
A panel of 4 experts on bladder cancer
A panel of 4 experts on bladder cancer
Wenxin (Vincent) Xu, MD
Patrick I. Borgen, MD
A panel of 5 experts on renal cell carcinoma
A panel of 5 experts on renal cell carcinoma
Kari Hacker, MD, PhD, NYU Grossman School of Medicine