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Durable responses were obtained with the immune checkpoint inhibitor nivolumab, with a manageable safety profile, in a phase II dose-ranging trial conducted in patients with previously treated metastatic renal cell carcinoma (mRCC).
The combination of abiraterone acetate and prednisone has demonstrated a statistically significant improvement in overall survival (OS) for men with metastatic castration-resistant prostate cancer (mCRPC) who had not received prior treatment with chemotherapy
Patients with unresectable melanoma had a significant improvement in the odds of survival when treated in first line with a combination of BRAF and MEK inhibitors, as opposed to anti-BRAF monotherapy
All patients with metastatic colorectal cancer should undergo RAS mutation testing to ensure optimal patient selection for EGFR inhibitor therapy.
Inhibiting BRAF and MEK at the same time improves progression-free survival (PFS) more so than BRAF inhibition alone in patients with BRAF V600 mutation-positive metastatic melanoma, according to results of a phase III placebo-controlled trial.
Latest Peer Exchange Discussions
Experts discuss the next-generation ALK inhibitors ceritinib and AP26113 as treatments for patients with non-small cell lung cancer. View Now
Panelists discuss the use of the newer hormonal agents abiraterone and enzalutamide for the treatment of patients with mCRPC. View Now
Brian Rini, MD, Janice Dutcher, MD, Daniel Heng, MD, MPH, and Charles Henderson, MD, examine factors practitioners consider when treating progressive renal cell carcinoma. View Now
In this discussion, panelists discuss the benefits of administering nab-paclitaxel as a treatment for patients with metastatic breast cancer. View Now
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Highlights From the 13th Annual International Congress on the Future of Breast Cancer®
Pancreatic Cancer: Novel and Emerging Approaches to Early Detection and Treatment
OncoLogue: Breast Cancer Cases
Update From ASCO: Advances in Immunotherapy for Non–Small Cell Lung Cancer and Melanoma