Dr. Wetzler on Autologous Transplantation in Ph+ALL

Meir Wetzler, MD
Published Online: Tuesday, December 18, 2012
Meir Wetzler, MD, Chief, Leukemia Section, Department of Medicine, Roswell Park Cancer Institute, explains the CALGB 10001 study analyzing autologous and allogeneic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL).

The authors of the study hypothesized that an imatinib and sequential chemotherapy regimen would allow for the collection of a patient’s normal hematopoietic stem cells not contaminated by residual BCR/ABL+ lymphoblasts and reduce the likelihood of relapse after an autologous transplantation.

The study found that autologous transplantation is a safe and effective alternative to allogeneic transplantation for patients with Ph+ALL.

Online CME Activities
Free CME from PER
Community Practice Connections™: 16th Annual International Lung Cancer Congress®
Community Practice Connections™: 14th Annual International Congress on the Future of Breast Cancer®
Oncology Consultations®: Integrating Molecular Testing into the Breast Cancer Treatment Paradigm
Role of the Nurse in Facilitating Adherence to Oral Therapies in Oncology Practice
More Reading