Conferences
Breast Cancers
GI Cancers
Gynecologic Cancer
Immunology News
Head & Neck
Hematology
Lymphoma
Leukemia
Lung Cancers
Melanoma
Prostate Cancer
Urology
CLL
Precision Medicine
More...
Giants

Dr. Wierda on the Treatment of Elderly CLL Patients

William G. Wierda, MD, PhD
Published Online: Wednesday, March 12, 2014
William G. Wierda, MD, PhD, professor, Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, discusses treatment recommendations for patients with chronic lymphocytic leukemia (CLL).

The CLL11 trial compared chlorambucil, chlorambucil plus rituximab, and chlorambucil plus obinutuzumab (GA101) in previously untreated patients with CLL and and preexisting medical conditions. The trial showed superiority for the chlorambucil plus obinutuzumab arm. To be eligible for this trial, patients needed to have a SEER score higher than 6, which reflects comorbidities associated with age (over age 65 or 70) or renal insufficiency.

Wierda says if an elderly patient who needs frontline therapy and is not appropriate for chemoimmunotherapy is seen at his practice, the first choice of treatment for the patient would be chlorambucil plus obinutuzumab.

Online CME Activities
Free CME from PER
Community Practice Connections: 12th Annual International Congress on Targeted Therapies in Cancer®
12th Annual School of Breast Oncology® Online
Advances in Next-Generation Sequencing in Precision Oncology
9th Annual Multidisciplinary Symposium on Head and Neck Cancer® Medical Crossfire®
More Reading
No Result Found
$auto_registration$