Dr. Weiss on Biomarkers in Head and Neck Cancer

Video

Jared Weiss, MD, assistant professor, UNC Lineberger Comprehensive Cancer Center, discusses biomarkers in head and neck cancer.

Jared Weiss, MD, assistant professor, UNC Lineberger Comprehensive Cancer Center, discusses biomarkers in head and neck cancer.

Currently, one of the only available biomarkers for head and neck cancer is HPV. If the cancer is driven by HPV, it has more curative potential. But, this is not the optimal indicator for choosing treatment for patients with head and neck cancer, according to Weiss.

In regard to immunotherapy efficacy, Weiss says HPV isn’t a good biomarker. PD-L1 biomarkers are also problematic for immunotherapy, but some studies on interferon gamma signatures appear promising.

Related Videos
Shivaani Kummar, MBBS, FACP, Margaret and Lester DeArmond Endowed Chair of Cancer Research, Professor and Division Head, Division of Hematology/Medical Oncology, Oregon Health & Science University School of Medicine; co-director, Center for Experimental Therapeutics, co-deputy director, Knight Cancer Institute
Andre Goy, MD
Wenxin (Vincent) Xu, MD,
Guenther Koehne, MD, PhD
Alessandro Villa, DDS, PhD, MPH
Joseph Mikhael, MD
Michael Richardson, MD
Minesh Mehta, MD
Ruben Olivares, MD
Phillip J. Koo, MD