Eribulin Gains EU Approval for Advanced Liposarcoma
The European Commission has approved eribulin mesylate (Halaven) as a treatment for patients with advanced or unresectable liposarcoma following anthracycline-based chemotherapy.
APRIL/BCMA Targeted Agent May Block Tumor Growth, Drug Resistance in Myeloma
Kenneth Anderson, MD, PhD, discusses the role of APRIL/BCMA and what potential the targeted agent BION-1301 may have in blocking multiple myeloma cell proliferation, as well as reducing drug resistance and immunosuppression in the tumor microenvironment.
Regorafenib Improves Survival in Liver Cancer
Regorafenib (Stivarga) improved overall survival versus best supportive care in patients with unresectable hepatocellular carcinoma who progressed after receiving sorafenib (Nexavar).
FDA Grants Olaratumab Priority Review for Soft Tissue Sarcoma
The FDA has granted the PDGFRα antagonist olaratumab a priority review for use in combination with doxorubicin for the treatment of patients with advanced soft tissue sarcoma who are not good candidates for radiotherapy or surgery.
FDA Grants Blinatumomab Priority Review for Pediatric Acute Lymphoblastic Leukemia
The FDA has granted a priority review to an application to expand the approval of blinatumomab (Blincyto) to include the treatment of pediatric and adolescent patients with Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia.
Steroid Use With Abiraterone Offers Multidimensional Benefits to Patients With mCRPC
Abiraterone acetate, alone or in combination with low-dose steroids, has been intensely investigated in recent years for the treatment of progressive CRPC in patients who have received prior chemotherapy or who were treatment-naïve.
Expert Shares Insight on Promising Entinostat/IL-2 Results in RCC
Robert Pili, MD, discusses the results and significance of an early-phase trial looking at the combination of entinostat and interleuken-2 and how it could shake up the treatment paradigm for renal cell carcinoma.
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