Breast Cancer Articles | Page 2

AKT Inhibitor May Overcome Chemotherapy Resistance in 2 Breast Cancer Subtypes
A novel inhibitor that targets the AKT node in the PI3K pathway may offer a treatment option in cases of resistance to chemotherapy in 2 patient populations: triple-negative breast cancer or ER-positive/HER2-negative breast cancer with certain molecular aberrations.
Reshma Mahtani, DO, discusses the tolerability of CDK 4/6 inhibitors for the treatment of patients with metastatic breast cancer.
Biosimilar Filgrastim Safety Confirmed in Analysis
EP2006, a filgrastim biosimilar, produced safety results equivalent to those observed with referent filgrastim in a combined analysis of 2 phase III breast cancer studies from the United States and Europe.
Trastuzumab Biosimilar Approaches European Approval
The European Medicines Agency’s Committee for Medicinal Products for Human Use has adopted a positive opinion for the marketing authorization of ABP 980, a biosimilar to trastuzumab. 
Traina Talks TNBC Treatment Evolution
Tiffany A. Traina, MD, discussed the potential for PARP inhibitors, as well as immunotherapy and antibody-drug conjugates, for the treatment of patients with triple-negative breast cancer.
Avoiding Unnecessary Surgery and Radiation in Low-Risk DCIS
Research suggests that many cases of DCIS have a low risk for progression and may not require surgical excision and radiation therapy.
Scarcity of Actionable Oncogenes Should Not Preclude Testing in Breast Cancer
Although much remains unknown about many mutations and test results rarely clarify the need for any particular response, panel testing has already demonstrated its cost value, which continues to increase every day.
Unlocking the Potential of Immunotherapy in Breast Cancer
A pair of trials that used checkpoint inhibitors as monotherapy reported lackluster overall response rates in breast cancer.
Optimizing HER2-Targeted Therapy
Sara Hurvitz, MD, and Sunil Verma, MD, share their expert insight on the latest groundbreaking developments in HER2-positive breast cancer.
An Early Voice for Breast Conservation Therapy Reflects on a Changing Field
As a trailblazer who helped breast cancer treatment evolve from radical mastectomy to the judicious use of radiation therapy with limited tumor removal, Samuel Hellman, MD, is considered one of the world's premier radiation oncologists.
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