Colorectal Cancer Articles

Neoadjuvant, Nonoperative Regimens Being Investigated in Rectal Cancer
Katherine Van Loon, MD, MPH, discusses the emerging use of neoadjuvant therapy and nonoperative approaches for patients with locally advanced rectal cancer.
Precision Medicine Impact Grows in GI Cancer Paradigm
Bert H. O’Neil, MD, discusses the role of molecular testing throughout GI cancers and highlights the current and developing treatment landscape for patients with colorectal cancer. 
Expert Sheds Light on Recent Advances in mCRC
Shubham Pant, MD, shares his insight on the future direction of the treatment landscape of colorectal cancer.
FDA Grants Nivolumab/Ipilimumab Priority Review for MSI-H/dMMR Colorectal Cancer
The FDA has granted a priority review to a supplemental biologics license application for nivolumab plus ipilimumab for the treatment of adult patients with microsatellite instability-high or mismatch repair deficient metastatic colorectal cancer following progression on a fluoropyrimidine, oxaliplatin, and irinotecan.
 
Immunotherapy, Sidedness Strategies Enhancing mCRC Treatment
Chloe E. Atreya, MD, PhD, discusses the latest treatment advances in mCRC, including tumor sidedness and emerging immunotherapy strategies.
Atezolizumab, Cobimetinib Combo Active in mCRC
Atezolizumab in combination with cobimetinib induced a 31% disease control rate in patients with heavily-pretreated metastatic colorectal cancer.
Venook Highlights Impact of IDEA Trial in Colon Cancer
Alan P. Venook, MD, discusses the significance of the findings of the international IDEA study investigating doses of FOLFOX for patients with colon cancer.
NCCN Recommends Regorafenib Dose Escalation in Metastatic CRC
The NCCN has updated its colorectal cancer (CRC) guidelines, recommending a weekly regorafenib dose-escalation strategy beginning at 80 mg and ending at 160 mg for previously treated patients with metastatic CRC.
Nut Consumption Linked to Survival Benefit in Colon Cancer
Patients with stage III colon cancer who ate at least 2 servings of nuts per week had superior disease-free survival and overall survival.
First Liver Transplant Surgery Performed in Patient With CRC Metastases
Although the standard-of-care treatment for patients with liver metastases developing from colorectal cancer is liver resection, only one-third of these patients are candidates for surgery.
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