Melanoma & Skin Cancer Articles

Immunotherapy Lessons Learned in Melanoma May Turn Tide in Other Tumors
The use of immunotherapy in cancer was solidified by the ample activity seen in patients with melanoma.
Cemiplimab Nears EU Approval for CSCC
The European Medicines Agency's Committee for Medicinal Products for Human Use issued a positive opinion recommending approval of cemiplimab for the treatment of adult patients with metastatic or locally advanced cutaneous squamous cell carcinoma who are not candidates for curative surgery or curative radiation, according to Regeneron Pharmaceuticals, the manufacturer of the PD-1 inhibitor.
Childhood Cancer Survivors at Increased Risk for Skin Cancers
Childhood cancer survivors who had lived 5 or more years from their primary malignancy are at an increased risk of developing skin cancer compared with the general population.
SITC Guidelines Provide a Fresh Look at Evolving Strategies for Melanoma
New therapeutic approaches for treating patients with earlier-stage melanoma who face a higher risk of recurrence are among the features of recently updated consensus guidelines from the Society for Immunotherapy of Cancer.
The European Medicines Agency’s Committee for Medicinal Products for Human Use has adopted a positive opinion for a new extended dosing schedule for pembrolizumab for all of the PD-1 inhibitor’s monotherapy indications in the European Union.
New Targeted Therapy Duo Provides Advantages in BRAF-Mutant Melanoma
Keith T. Flaherty, MD, discussed the distinguishing features of the combination of encorafenib with binimetinib as well as some next steps, including the question of whether the regimen eventually could move to the adjuvant setting.
Select patients with melanoma who consume a diet rich in fiber could see an improved response to treatment with immunotherapy.
FDA Approves Adjuvant Pembrolizumab in Stage III Melanoma
The FDA has approved the PD-1 inhibitor pembrolizumab for the adjuvant treatment of patients with high-risk stage III melanoma with lymph node involvement following complete resection. 
Pembrolizumab Granted 5 Additional Approvals in Japan
The Japan Pharmaceuticals and Medical Devices Agency has approved pembrolizumab for 5 new indications, including melanoma, advanced microsatellite instability-high tumors, and 3 expanded uses in advanced non–small cell lung cancer.
FDA Approves Pembrolizumab in Merkel Cell Carcinoma
The FDA has granted an accelerated approval to pembrolizumab for the treatment of adult and pediatric patients with recurrent locally advanced or metastatic Merkel cell carcinoma.
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