Ramona Dadu, MD, assistant professor, Department of Endocrine Neoplasia and Hormonal Disorders, MD Anderson Cancer Center, discusses the results of a pilot study that examined the efficacy of calcium aluminosilicate clay (CASAD)
for reducing medullary thyroid cancer (MTC)- related diarrhea.
MTC-related diarrhea can reduce patients’ quality of life. While there are other drugs on the market that can be used to treat MTC-related diarrhea, they generally cause side effects. CASAD is all natural and used to treat diarrhea-related side effects in other cancer patients.
Dadu says 8 out of 9 patients discontinued the current anti-diarrhea medication they were taking after taking CASAD. Also, 7 out of 10 patients were evaluable for the primary endpoint and 4 out of 7 patients met the primary endpoint of reducing the severity of diarrhea.
The best results were seen in between 3 days and 21 days, Dadu says. Every patient on the study responded, with between a 9% and 99% reduction in their frequency of bowel movements. All patients also reported a significant improvement in their quality of life after taking CASAD, Dadu says.
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