Manuela Schmidinger, MD, medical oncologist, Medical University of Vienna, discusses the management of side effects from targeted agents in renal cell cancer, including hypertension, diarrhea, and hand-foot syndrome.
Hypertension is a common side effect, Schmidinger says, and is an important biomarker for response to treatment. Schmidinger says it is crucial to inform a patient prior to treatment, obtain a daily blood pressure reading in the first three months, and correct blood pressure.
Diarrhea affects a patient's quality of life greatly and a physician needs to provide prophylactic measures, Schmidinger says. A physician must also consider that diarrhea may be the result of drug-induced pancreatic insufficiency.
Hand-foot syndrome is also a common side effect and requires a pedicure before treatment. Schmidinger says following the pedicure, an application of local fatty ointments should be applied on a daily basis.
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