Dr. Scholz on Using Abiraterone in mCRPC

Mark Scholz, MD
Published: Wednesday, Mar 04, 2015



Mark Scholz, MD, medical director, Prostate Oncology Specialists, discusses the final analysis of the COU-AA-302 study, which compared abiraterone acetate to prednisone alone in patients with metastatic castration-resistant prostate cancer (mCRPC).

The COU-AA-302 study demonstrated an unequivocal survival advantage for abiraterone compared to placebo, Scholz says. This is a revolutionary development, he adds, because the standard of care for this disease has been docetaxel.

In comparing abiraterone and docetaxel, Scholz finds there is equal efficacy. However, a substantial reduction in toxicity and convenience of administration exists in using abiraterone.

Almost universally within Prostate Oncology Specialists, patients with mCRPC are being treated with abiraterone prior to docetaxel, in light of these findings.

<<< View more from the 2015 GU Cancer Symposium



Mark Scholz, MD, medical director, Prostate Oncology Specialists, discusses the final analysis of the COU-AA-302 study, which compared abiraterone acetate to prednisone alone in patients with metastatic castration-resistant prostate cancer (mCRPC).

The COU-AA-302 study demonstrated an unequivocal survival advantage for abiraterone compared to placebo, Scholz says. This is a revolutionary development, he adds, because the standard of care for this disease has been docetaxel.

In comparing abiraterone and docetaxel, Scholz finds there is equal efficacy. However, a substantial reduction in toxicity and convenience of administration exists in using abiraterone.

Almost universally within Prostate Oncology Specialists, patients with mCRPC are being treated with abiraterone prior to docetaxel, in light of these findings.

<<< View more from the 2015 GU Cancer Symposium


View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: Personalized Sequencing in Castration-Resistant Prostate Cancer: Bridging the Latest Evidence to the Bedside in Clinical ManagementAug 25, 20181.5
Community Practice Connections™: Precision Medicine for Community Oncologists: Assessing the Role of Tumor-Testing Technologies in Cancer CareNov 30, 20181.0
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