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Dr. Balar on Results of KEYNOTE-052 in Urothelial Cancer

Arjun Balar, MD
Published: Friday, Feb 17, 2017



Arjun Balar, MD, director, Genitourinary Medical Oncology Progam, NYU Langone Medical Center, discusses the results from the KEYNOTE-052 trial in cisplatin-ineligible advanced urothelial carcinoma.

In this study of 370 patients, 200 mg of pembrolizumab (Keytruda) was administered every 3 weeks. At week 9, imaging was performed and then every 6 weeks for the first year and every 12 weeks beyond that.

The study met its primary end point of overall response rate, which was 27% among patients with a greater than 4-month follow-up. The complete response rate was 6%.

Balar concludes that this study confirms the effectiveness and durability of pembrolizumab in cisplatin-ineligible patients with urothelial carcinoma.
 


Arjun Balar, MD, director, Genitourinary Medical Oncology Progam, NYU Langone Medical Center, discusses the results from the KEYNOTE-052 trial in cisplatin-ineligible advanced urothelial carcinoma.

In this study of 370 patients, 200 mg of pembrolizumab (Keytruda) was administered every 3 weeks. At week 9, imaging was performed and then every 6 weeks for the first year and every 12 weeks beyond that.

The study met its primary end point of overall response rate, which was 27% among patients with a greater than 4-month follow-up. The complete response rate was 6%.

Balar concludes that this study confirms the effectiveness and durability of pembrolizumab in cisplatin-ineligible patients with urothelial carcinoma.
 



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