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Dr. Slovin on Prostate Cancer Immunotherapy Evolution

Susan F. Slovin, MD, PhD
Published: Monday, Mar 18, 2013

Susan F. Slovin, MD, PhD, an associate member in the Genitourinary Oncology Service at the Memorial Sloan-Kettering Cancer Center, summarizes the development of an effective immunotherapy for the treatment of men with prostate cancer.

The initial phase I/II trials examining immunotherapeutic approaches in prostate cancer were not successful, Slovin states. Many of these agents were tested as single agents and were largely ineffective. However, these early trials successfully demonstrated that an immune response could be elicited in patients with prostate cancer.

Now for the first time, Slovin notes, with sipuleucel-T (Provenge), an immune product vaccine has extended overall survival. By and large, Slovin notes, researchers are still examining the mechanism of action for sipuleucel-T, to further understand how the agent successfully generates a biologic response.

<<< View coverage from the 2013 IPCC

Susan F. Slovin, MD, PhD, an associate member in the Genitourinary Oncology Service at the Memorial Sloan-Kettering Cancer Center, summarizes the development of an effective immunotherapy for the treatment of men with prostate cancer.

The initial phase I/II trials examining immunotherapeutic approaches in prostate cancer were not successful, Slovin states. Many of these agents were tested as single agents and were largely ineffective. However, these early trials successfully demonstrated that an immune response could be elicited in patients with prostate cancer.

Now for the first time, Slovin notes, with sipuleucel-T (Provenge), an immune product vaccine has extended overall survival. By and large, Slovin notes, researchers are still examining the mechanism of action for sipuleucel-T, to further understand how the agent successfully generates a biologic response.

<<< View coverage from the 2013 IPCC




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TitleExpiration DateCME Credits
Community Practice Connections™: Personalized Sequencing in Castration-Resistant Prostate Cancer: Bridging the Latest Evidence to the Bedside in Clinical ManagementAug 25, 20181.5
Community Practice Connections™: Precision Medicine for Community Oncologists: Assessing the Role of Tumor-Testing Technologies in Cancer CareNov 30, 20181.0
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