Dr. Baselga on Biomarker Research for Breast Cancer

Jose Baselga, MD, PhD
Published: Friday, Sep 15, 2017



José Baselga, MD, PhD, medical oncologist at Memorial Sloan Kettering Cancer Center, discusses biomarker research for patients with breast cancer.

According to Baselga, the community is still in the process of validating some of the targets. There is a need to incorporate next-generation sequencing platforms into clinical practice.

It no longer makes sense to only check for estrogen receptor mutations or HER2 proliferation, but rather to look at comprehensive panels of genes. This will open opportunities for new ways to detect these abnormalities. For example, researchers are very excited by the prospect of developing liquid biopsies, which have the capacity to look for these DNA alterations in the blood. That would be a non-invasive approach, states Baselga.

<<< More from the Lynn Sage Breast Cancer Symposium


José Baselga, MD, PhD, medical oncologist at Memorial Sloan Kettering Cancer Center, discusses biomarker research for patients with breast cancer.

According to Baselga, the community is still in the process of validating some of the targets. There is a need to incorporate next-generation sequencing platforms into clinical practice.

It no longer makes sense to only check for estrogen receptor mutations or HER2 proliferation, but rather to look at comprehensive panels of genes. This will open opportunities for new ways to detect these abnormalities. For example, researchers are very excited by the prospect of developing liquid biopsies, which have the capacity to look for these DNA alterations in the blood. That would be a non-invasive approach, states Baselga.

<<< More from the Lynn Sage Breast Cancer Symposium

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Online CME Activities
TitleExpiration DateCME Credits
Real-World Evidence to Inform Treatment and Management of ER+ Metastatic Breast CancerDec 31, 20191.0
Medical Crossfire®: A Critical Assessment of Current and Emerging Data Sets to Move Treatment of Triple-Negative Breast Cancer ForwardJan 31, 20201.0
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