Erin McMenamin on HPV-related Head & Neck Cancer

Erin McMenamin, MSN
Published: Sunday, May 06, 2012

Erin McMenamin, MSN, Radiation Oncology, Hospital of the University of Pennsylvania, discusses the prognosis for patients with human papillomavirus (HPV)-positive squamous cell carcinoma of the head and neck.

HPV-positive head and neck tumors generally have a better prognosis than HPV-negative tumors. HPV-positive patients that are non-smokers or have smoked less than 10 year with low nodal involvement are at low-risk of recurrence. However, those that are HPV-positive, smoke, and have high nodal involvement are at high-risk of recurrence.

Patients with HPV-negative head and neck cancer are generally high-risk patients, since this form of cancer is commonly a direct result of smoking, which alters the histology of the oral cavity making it more susceptible to recurrence or other primary tumors. The lowest risk level an HPV-negative tumor is able to achieve is intermediate, for T1 or T2 sized tumors.

<<< View more from the 2012 ONS Congress

Erin McMenamin, MSN, Radiation Oncology, Hospital of the University of Pennsylvania, discusses the prognosis for patients with human papillomavirus (HPV)-positive squamous cell carcinoma of the head and neck.

HPV-positive head and neck tumors generally have a better prognosis than HPV-negative tumors. HPV-positive patients that are non-smokers or have smoked less than 10 year with low nodal involvement are at low-risk of recurrence. However, those that are HPV-positive, smoke, and have high nodal involvement are at high-risk of recurrence.

Patients with HPV-negative head and neck cancer are generally high-risk patients, since this form of cancer is commonly a direct result of smoking, which alters the histology of the oral cavity making it more susceptible to recurrence or other primary tumors. The lowest risk level an HPV-negative tumor is able to achieve is intermediate, for T1 or T2 sized tumors.

<<< View more from the 2012 ONS Congress


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TitleExpiration DateCME Credits
Clinical Interchange™: Translating Research to Inform Changing Paradigms: Assessment of Emerging Immuno-Oncology Strategies and Combinations across Lung, Head and Neck, and Bladder CancersOct 31, 20182.0
Community Practice Connections™: Precision Medicine for Community Oncologists: Assessing the Role of Tumor-Testing Technologies in Cancer CareNov 30, 20181.0
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