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Shridar Ganesan, MD, PhD, discusses the current limitations and advantages of leveraging circulating-tumor DNA to detect minimal residual disease in patients with cancer, as well as how ctDNA assays may address mechanisms of resistance in clinical practice.

Dr Ganesan on the Use of ctDNA Assays For MRD Detection in Cancer Care

M. Hamza Habib, MD, JD, MBA, FACP, FAAHPM, FRCPI, MRCP, discusses the development of novel technology-based strategies to improve palliative cancer for patients with cancer. 

Dr Habib on Developments in Palliative Care For Patients With Cancer

Patrick Boland, MD, discusses the development of therapeutic strategies targeting KRAS G12C mutations in colorectal cancer.
 

Dr Boland on the Emergence of KRAS G12C Inhibitors in mCRC

Haejin In, MD, MPH, MBA, FACS, FSSO, discusses the increased incidence of gastric cancer in minority patient populations, highlighting the disparities that lead to these patient outcomes in the United States.

Dr In on the Increased Incidence of Gastric Cancer in Minority Patient Populations

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joined MJH Life Sciences in 2016 and has since held several positions within the company. She helped launch the rapidly growing infectious disease news resource 

, and now serves as the main digital news writer for 

. Prior to working at the company, she served as lead copywriter and marketing coordinator at The Strand Theater. Email: krosa@onclive.com

Articles

The triplet combination of sintilimab, chidamide, and bevacizumab resulted in a high 18-week progression-free survival rate with a favorable toxicity profile in patients with microsatellite stable or mismatch repair–proficient metastatic colorectal cancer, according to data from the phase 2 CAPability-01 trial.

Sintilimab Triplet Demonstrates Efficacy With Acceptable Safety in pMMR/MSS CRC

Lyudmila A. Bazhenova, MD, expanded on key considerations when navigating the use of perioperative immunotherapy for patients with or without oncogenically-driven lung cancers, the importance of multidisciplinary collaboration when deciding on a treatment plan, and the need for increased and earlier implementation of biomarker testing in all patients with lung cancer. 

Multidisciplinary Collaboration and Molecular Testing Are Integral to Treatment Decision-Making in NSCLC

Pembrolizumab continued to demonstrate at trend toward improved overall survival compared with chemotherapy in patients with microsatellite instability–high or mismatch repair–deficient metastatic colorectal cancer. 

First-Line Pembrolizumab Demonstrates Durable Clinical Benefit in MSI-H/dMMR mCRC

Caroline Seymour is your initial point of contact for the 

™. She joined the company in 2018 as an assistant editor, with expertise in video production and print/digital publication. Email: 

The FDA has granted fast track designation to zotatifin for use in combination with fulvestrant and abemaciclib as second- or third-line therapy for the treatment of patients with estrogen receptor-positive, HER2-negative advanced or metastatic breast cancer with disease progression following treatment with endocrine therapy and a CDK4/6 inhibitor.

FDA Grants Fast Track Designation to Zotatifin Plus Fulvestrant/Abemaciclib in ER+/HER2– Breast Cancer

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Sound Bites

Predictive Biomarkers for Treatment With Amivantamab Plus Lazertinib Among EGFR-Mutated NSCLC in the Post-Osimertinib Setting: Analysis of Tissue IHC and ctDNA NGS 

Tissue and Plasma-Based Mechanisms of Resistance to First-Line Osimertinib in EGFR-Mutant NSCLC: A Multi-Institutional Cohort

Real-World Testing and Treatment Patterns Among Patients With Stage IV NSCLC: A Retrospective Observational Study

Contemporary Biomarker Testing Rates in Both Early and Advanced NSCLC: Results From the MYLUNG Pragmatic Study

What is NGS Testing?

What is DNA and RNA Testing in Biomarker Testing?

Why Are You Choosing a Certain Testing Platform in Biomarker Testing?

How Do You Explain Adjuvant Therapy in NSCLC?

When Should Patients With NSCLC be Referred to Thoracic Surgeons in Specialized Centers of Care?

NSCLC

Expert Sound Bites

Predictive Biomarkers for Treatment With Amivantamab Plus Lazertinib Among EGFR-Mutated NSCLC in the Post-Osimertinib Setting: Analysis of Tissue IHC and ctDNA NGS

Expert Sound Bites

Tissue and Plasma-Based Mechanisms of Resistance to First-Line Osimertinib in EGFR-Mutant NSCLC: A Multi-Institutional Cohort

Predictive Biomarkers for Treatment With Amivantamab Plus Lazertinib Among EGFR-Mutated NSCLC in the Post-Osimertinib Setting: Analysis of Tissue IHC and ctDNA NGS

Real-World Testing and Treatment Patterns Among Patients With Stage IV NSCLC: A Retrospective Observational Study

Contemporary Biomarker Testing Rates in Both Early and Advanced NSCLC: Results From the MYLUNG Pragmatic Study

What is NGS Testing?

What is DNA and RNA Testing in Biomarker Testing?

Why Are You Choosing a Certain Testing Platform in Biomarker Testing?

How Do You Explain Adjuvant Therapy in NSCLC?

When Should Patients With NSCLC be Referred to Thoracic Surgeons in Specialized Centers of Care?

What are the Benefits and Side Effects of TKIs?

What is a Biomarker in the Context of Tumors?

What is a Gene Mutation and a Gene Fusion?

What is a Chromosomal Rearrangement?

How Do You Explain Neoadjuvant Therapy in NSCLC?

What are Challenges Around Access to Testing?

What are the Benefits and Side Effects of Immunotherapy?