Dr. Arteaga on PI3K Pathway Inhibitors

Carlos Arteaga
Published: Tuesday, Jan 06, 2015



Carlos Arteaga, MD, assistant director, Clinical Research, director, Breast Cancer program, Vanderbilt-Ingram Cancer Center, discusses the PI3K pathway and the role of therapeutic inhibitors in reducing the progression of breast cancer.

The PI3K pathway itself can be mutated at different levels and different genes that are involved in the pathway can be mutated and altered, says Arteaga. Several inhibitors are in clinical development that hit the pathway at multiple points.

Arteaga predicts that the use of these inhibitors could become a standard of care in the near future.



Carlos Arteaga, MD, assistant director, Clinical Research, director, Breast Cancer program, Vanderbilt-Ingram Cancer Center, discusses the PI3K pathway and the role of therapeutic inhibitors in reducing the progression of breast cancer.

The PI3K pathway itself can be mutated at different levels and different genes that are involved in the pathway can be mutated and altered, says Arteaga. Several inhibitors are in clinical development that hit the pathway at multiple points.

Arteaga predicts that the use of these inhibitors could become a standard of care in the near future.


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Clinical Interchange™: Translating Research to Inform Changing Paradigms: Assessment of Emerging Immuno-Oncology Strategies and Combinations across Lung, Head and Neck, and Bladder CancersOct 31, 20182.0
Community Practice Connections: Oncology Best Practice™ Targeting Cell Cycle Progression: The Latest Advances on CDK4/6 Inhibition in Metastatic Breast CancerOct 31, 20181.0
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