Dr. Chari on Transplant Eligibility in Multiple Myeloma

Video

In Partnership With:

Ajai Chari, MD, discusses transplant eligibility in multiple myeloma.

Ajai Chari, MD, associate professor, hematology and medical oncology, Mount Sinai Hospital, discusses transplant eligibility in multiple myeloma.

Typically, fit patients under the age of 70 are considered transplant eligible, says Chari. Patients with comorbidities that include an ejection fraction >50% or a FEV1/FVC ratio >50% are typically not eligible for transplant, he adds. Notably, renal failure and dialysis dependence are not exclusion criteria for transplant.

Determining transplant eligibility in older patients is more challenging, says Chari. Patients who respond well to induction therapy with limited toxicity could have durable responses with maintenance therapy and may not need transplant. Conversely, patients who do not respond well to induction therapy, or who experience increased toxicity should be considered for transplant, concludes Chari.

Related Videos
Ricardo D. Parrondo, MD, hematologist/oncologist, Mayo Clinic
Ilyas Sahin, MD
Raj Singh, MD
Jaime R. Merchán, MD, professor, co-leader, Translational and Clinical Oncology Research Program, director, Phase 1 Clinical Trials Program, Department of Medicine, Division of Medical Oncology, the University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center
Saad J. Kenderian, MB, CHB
Tycel Phillips, MD
Minesh Mehta, MD
Shivaani Kummar, MBBS, FACP, Margaret and Lester DeArmond Endowed Chair of Cancer Research, Professor and Division Head, Division of Hematology/Medical Oncology, Oregon Health & Science University School of Medicine; co-director, Center for Experimental Therapeutics, co-deputy director, Knight Cancer Institute
Andre Goy, MD
Wenxin (Vincent) Xu, MD,