Dr. Epperla on Treatment Following Ibrutinib in MCL

Narendranath Epperla, MBBS, MS
Published: Wednesday, Nov 01, 2017



Narendranath Epperla, MBBS, MS, hematologist, The Ohio State University (OSU) Comprehensive Cancer Center, assistant professor in internal medicine, OSU, discusses the next steps for patients with mantle cell lymphoma (MCL) who fail ibrutinib (Imbruvica).

Patients who fail ibrutinib have poor results, with the median survival being a few months. As of today, there is no breakthrough treatment for patients who fail ibrutinib, which is an urgent unmet need, states Epperla.

There are ongoing combination trials investigating ibrutinib with CDK4/6 inhibitors to determine if that can overcome resistance, explains Epperla.
 


Narendranath Epperla, MBBS, MS, hematologist, The Ohio State University (OSU) Comprehensive Cancer Center, assistant professor in internal medicine, OSU, discusses the next steps for patients with mantle cell lymphoma (MCL) who fail ibrutinib (Imbruvica).

Patients who fail ibrutinib have poor results, with the median survival being a few months. As of today, there is no breakthrough treatment for patients who fail ibrutinib, which is an urgent unmet need, states Epperla.

There are ongoing combination trials investigating ibrutinib with CDK4/6 inhibitors to determine if that can overcome resistance, explains Epperla.
 

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: Oncology Best Practice™: Choosing Therapies for Patients with EGFR-mutant Lung Cancers: More Options... More Decisions... Better OutcomesApr 27, 20182.0
Community Practice Connections™: 21st Annual International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas, and MyelomaApr 27, 20182.0
Publication Bottom Border
Border Publication
x