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Dr. Fitch Discusses Dose Escalation of Radiation in Prostate Cancer

Dwight L. Fitch, MD
Published: Friday, Sep 26, 2014

Dwight L. Fitch, MD, Radiation Oncologist, 21st Century Oncology in Bradenton, Florida, discusses dose modifications for radiation therapy in patients with prostate cancer.

Over the last 10 years, the dose of radiation for prostate cancer has gone from 70 Gy to 79-81 Gy. This dose increase lowers PSA failure while increasing prostate cancer control; however, it remains unclear whether it improves survival, Fitch notes. Additionally, the increased dose results in added toxicity. 

A study presented at the 2014 ASTRO Annual Meeting attempted to address these concern. Overall, the analysis showed that patients could be treated at a few fractions under the maximum tolerated dose to help decrease toxicities, without compromising PSA control and survival, Fitch says.
 
Dwight L. Fitch, MD, Radiation Oncologist, 21st Century Oncology in Bradenton, Florida, discusses dose modifications for radiation therapy in patients with prostate cancer.

Over the last 10 years, the dose of radiation for prostate cancer has gone from 70 Gy to 79-81 Gy. This dose increase lowers PSA failure while increasing prostate cancer control; however, it remains unclear whether it improves survival, Fitch notes. Additionally, the increased dose results in added toxicity. 

A study presented at the 2014 ASTRO Annual Meeting attempted to address these concern. Overall, the analysis showed that patients could be treated at a few fractions under the maximum tolerated dose to help decrease toxicities, without compromising PSA control and survival, Fitch says.
 



View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: Personalized Sequencing in Castration-Resistant Prostate Cancer: Bridging the Latest Evidence to the Bedside in Clinical ManagementAug 25, 20181.5
Community Practice Connections™: Precision Medicine for Community Oncologists: Assessing the Role of Tumor-Testing Technologies in Cancer CareNov 30, 20181.0
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