Dr. Gasparetto on Next Steps With Selinexor and Daratumumab in Multiple Myeloma

Cristina Gasparetto, MD
Published: Monday, Jan 08, 2018



Cristina Gasparetto, MD, assistant professor of medicine, member of the Duke Cancer Institute, discusses the next steps with selinexor and daratumumab (Darzalex) in multiple myeloma.

In a phase lb study, the combination of selinexor and daratumumab was evaluated in patients with relapsed/refractory multiple myeloma who were previously exposed to proteasome inhibitors and immunomodulatory drugs.

This combination will move onto a phase II study with more patients, says Gasparetto, in order to effectively evaluate response, side effects, and efficacy.
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Cristina Gasparetto, MD, assistant professor of medicine, member of the Duke Cancer Institute, discusses the next steps with selinexor and daratumumab (Darzalex) in multiple myeloma.

In a phase lb study, the combination of selinexor and daratumumab was evaluated in patients with relapsed/refractory multiple myeloma who were previously exposed to proteasome inhibitors and immunomodulatory drugs.

This combination will move onto a phase II study with more patients, says Gasparetto, in order to effectively evaluate response, side effects, and efficacy.

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