Dr. Jonasch on Alternative Sunitinib Scheduling for mRCC

Eric Jonasch, MD
Published: Friday, Mar 10, 2017



Eric Jonasch, MD, professor, The University of Texas MD Anderson Cancer Center, discusses the phase II study of alternative sunitinib (Sutent) scheduling in patients with metastatic renal cell carcinoma (mRCC).

This study was testing the hypothesis that changing the schedule of sunitinib would allow patients to have lower toxicity rates and improve time on treatment and efficacy, states Jonasch. The primary endpoint was decreased grade 3 toxicity, which was not met during this study.

The patients who stayed on the study for a long period of time experienced a progression-free survival of 19 months and a response rate of 55%.
 


Eric Jonasch, MD, professor, The University of Texas MD Anderson Cancer Center, discusses the phase II study of alternative sunitinib (Sutent) scheduling in patients with metastatic renal cell carcinoma (mRCC).

This study was testing the hypothesis that changing the schedule of sunitinib would allow patients to have lower toxicity rates and improve time on treatment and efficacy, states Jonasch. The primary endpoint was decreased grade 3 toxicity, which was not met during this study.

The patients who stayed on the study for a long period of time experienced a progression-free survival of 19 months and a response rate of 55%.
 

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Medical Crossfire®: Key Questions for the Use of Immunotherapy Throughout the Disease Continuum for NSCLC in an Era of Rapid DevelopmentSep 29, 20181.5
Provider and Caregiver Connection™: Addressing Patient Concerns While Managing GlioblastomaSep 29, 20182.0
Publication Bottom Border
Border Publication
x