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Dr. Li Discusses the EML4-ALK Fusion Gene

Tianhong Li, MD, PhD
Published: Friday, Sep 09, 2011

Tianhong (Tina) Li, MD, PhD, assistant professor, co-director of Phase I Program, UC Davis Cancer Center, discusses the EML4-ALK fusion gene, which is created by translocation of the EML4 and ALK genes. The rearrangement of these two genes is spurred by an overexpression of tyrosine kinase in the ALK gene.

There are many driver genes with fusion partners, in lung cancer the EML4-ALK fusion is the most common. There are over 20 different variants of the ALK driver gene, but, the EML4-ALK fusion is the most common by far.
Tianhong (Tina) Li, MD, PhD, assistant professor, co-director of Phase I Program, UC Davis Cancer Center, discusses the EML4-ALK fusion gene, which is created by translocation of the EML4 and ALK genes. The rearrangement of these two genes is spurred by an overexpression of tyrosine kinase in the ALK gene.

There are many driver genes with fusion partners, in lung cancer the EML4-ALK fusion is the most common. There are over 20 different variants of the ALK driver gene, but, the EML4-ALK fusion is the most common by far.

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: 18th Annual International Lung Cancer Congress®Oct 31, 20181.5
Clinical Interchange™: Translating Research to Inform Changing Paradigms: Assessment of Emerging Immuno-Oncology Strategies and Combinations across Lung, Head and Neck, and Bladder CancersOct 31, 20182.0
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