Dr. Neal on Exciting Advancements in the Field of Lung Cancer

Joel Neal, MD, PhD
Published: Tuesday, Sep 27, 2016



Joel Neal, MD, PhD, assistant professor of Medicine (Oncology), Stanford University Medical Center, discusses exciting advancements in the field of lung cancer over the past few years. Neal shared these insights during an interview at the 2016 International Association for the Study of Lung Cancer Multidisciplinary Symposium on Thoracic Oncology.

Immunotherapy has had a significant role in propelling the field forward, Neal explains. While patient selection is improving, researchers still need to actively explore who is not appropriate to receive these therapies. Additional questions revolve around who should receive immunotherapy in first-line, as well as in second- and third-line settings.

Targeted therapies are also making an impact, Neal says. For patients with EGFR-mutant lung cancer, the T790M-targeted agent is osimertinib (Tagrisso). Testing for this resistance mutation has also become an important topic in the field. For ALK-positive patients, alectinib (Alecensa) could be a promising agent—potentially in the frontline setting, he adds.


Joel Neal, MD, PhD, assistant professor of Medicine (Oncology), Stanford University Medical Center, discusses exciting advancements in the field of lung cancer over the past few years. Neal shared these insights during an interview at the 2016 International Association for the Study of Lung Cancer Multidisciplinary Symposium on Thoracic Oncology.

Immunotherapy has had a significant role in propelling the field forward, Neal explains. While patient selection is improving, researchers still need to actively explore who is not appropriate to receive these therapies. Additional questions revolve around who should receive immunotherapy in first-line, as well as in second- and third-line settings.

Targeted therapies are also making an impact, Neal says. For patients with EGFR-mutant lung cancer, the T790M-targeted agent is osimertinib (Tagrisso). Testing for this resistance mutation has also become an important topic in the field. For ALK-positive patients, alectinib (Alecensa) could be a promising agent—potentially in the frontline setting, he adds.

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Community Practice Connections™: ALK-Positive NSCLC: Emerging Strategies to Inform Sequencing, Optimize Outcomes, and Address Unmet Clinical Needs Along the Disease ContinuumAug 29, 20181.5
Community Practice Connections™: Oncogenic Tumor Board in Advanced NSCLC: Leveraging Actionable Mutations Along the Disease Continuum to Optimize Patient OutcomesAug 30, 20182.0
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