Dr. Traina on the FDA Approval of Trastuzumab Deruxtecan for HER2+ Breast Cancer

Tiffany A. Traina, MD
Published: Friday, Dec 20, 2019



Tiffany A. Traina, MD, medical oncologist, Memorial Sloan Kettering Cancer Center, discusses the FDA approval of fam-trastuzumab deruxtecan-nxki (Enhertu; DS-8201) for patients with HER2-positive, locally advanced, or metastatic breast cancer who have been treated with trastuzumab (Herceptin) and pertuzumab (Perjeta) and have disease progression after ado-trastuzumab emtansine (T-DM1; Kadcyla).

This approval is based on an ongoing, dose escalation/expansion phase I study, preliminary data from which were presented at the 2017 ASCO Annual Meeting by Toshihiko Doi, MD, PhD, of Japan’s National Cancer Center Hospital East.
 
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Tiffany A. Traina, MD, medical oncologist, Memorial Sloan Kettering Cancer Center, discusses the FDA approval of fam-trastuzumab deruxtecan-nxki (Enhertu; DS-8201) for patients with HER2-positive, locally advanced, or metastatic breast cancer who have been treated with trastuzumab (Herceptin) and pertuzumab (Perjeta) and have disease progression after ado-trastuzumab emtansine (T-DM1; Kadcyla).

This approval is based on an ongoing, dose escalation/expansion phase I study, preliminary data from which were presented at the 2017 ASCO Annual Meeting by Toshihiko Doi, MD, PhD, of Japan’s National Cancer Center Hospital East.
 

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