Dr. Kasper on Imatinib Versus Sorafenib in Sarcoma
Bernd Kasper, MD, PhD
Bernd Kasper, MD, PhD, professor, Universitätsmedizin Mannheim, Mannheim, discusses imatinib (Gleevac) versus sorafenib (Nexavar) as treatments for patients with sarcoma.
There are 4 studies which used imatinib, explains Kasper. The most positive results from those studies demonstrate a treatment duration of 2 years and an overall response rate of 90%.
There is a retrospective study with sorafenib (Nexavar), which determined an overall response rate of 80% but demonstrated more toxicities than imatinib for patients being treated with sarcoma.