To Radiation With Love: A Bench-to-Bedside Immunotherapy Story

Chandan Guha, MBBS, PhD
Published: Friday, May 18, 2018
dan-duncanChandan Guha, MBBS, PhD
 
Chandan Guha, MBBS, PhD
Founding Director, Albert
Einstein College of Medicine
Institute of Onco-Physics
Vice Chair, Department of Radiation Oncology
Montefiore Einstein Center
for Cancer Care
Albert Einstein Cancer Center
Bronx, New York
Strategic Partnership
More than 20 years ago, I was a younger immunologist training in radiation oncology at Montefiore Health System, Albert Einstein College of Medicine, in Bronx, New York, one of the country’s leading institutions for medical education, basic research, and clinical investigation.

 

Figure. Mounting a Dual Attack

Under normal conditions, DCs are minimally present in circulating blood. We reasoned that circulating DCs could ingest dying tumor cells after RT and present specific tumor antigens to T cells in tumor-draining lymph nodes, thereby activating a tumor-specific immune response.
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View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Online Medical Crossfire®: 5th Annual Miami Lung Cancer ConferenceMay 30, 20196.5
Community Practice Connections™: Practical Application of Sequencing for EGFR-Mutant Lung Cancers: A Focus on Recent Evidence and Key Next Steps in TrialsJun 29, 20192.5
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