Many cellular processes are activated in AR signaling, with the MAPK and PI3K-Akt pathways, illustrated at right, among the best characterized networks. The process of androgen metabolism through testosterone is shown at left.
AR indicates androgen receptor; ARE, androgen response elements; PIP, phosphatidylinositol phosphate; DHEA, dehydroepiandrosterone; DHT, dihydrotestosterone; hsp, heat shock protein; P, phosphorylation. Adapted from Girling JS et al. Pathogenesis of prostate cancer and hormone refractory prostate cancer. Indian J Urol. 2007;23(1):35-42.
|Title||Expiration Date||CME Credits|
|Enduring CME activity from the School of Breast Oncology®: 2018 Mid-Year Video Update||Sep 28, 2019||2.0|
|Community Practice Connections™: 2nd Annual School of Nursing Oncology™||Sep 28, 2019||1.5|