Cancer Research Moves Beyond the Original Hallmarks of Cancer

Jane de Lartigue, PhD
Published: Wednesday, Jun 20, 2012

Strategies Targeting the Hallmarks

of Cancer

Strategies Targeting the Hallmarks of Cancer Click to enlarge.

This figure illustrates some of the many approaches employed in developing therapeutics targeted to the known and emerging hallmarks of cancer.



EGFR indicates epidermal growth factor receptor; CTLA4, cytotoxic T lymphocyte-associated antigen 4; mAb, monoclonal antibody; HGF, hepatocyte growth factor; VEGF, vascular endothelial growth factor; PARP, poly-(ADP ribose) polymerase.


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