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Adjuvant Radiotherapy Improves Survival in Rare Sarcoma Subtype

Jason Harris
Published: Friday, May 19, 2017

Adjuvant radiotherapy (RT) was associated with improved survival for patients with non-retroperitoneal abdominal soft tissue sarcomas (NRA-STS), but the addition of chemotherapy did not confer a similar survival benefit. The results, produced from an analysis of data collected in the National Cancer Data Base, were published in the Asia-Pacific Journal of Clinical Oncology.

Positive margins were detected in 455 patients and were not correlated with tumor size. Margin positivity decreased 5-year survival by 19%, from an HR of 0.54 (95% CI, 0.49-0.58) to an HR of 0.35 (95% CI, 0.3-0.4). The use of radiotherapy in the presence of positive margins was associated with reduced mortality (HR, 23%; 95% CI, 0.59-0.97).
Green WR, Chokshi R, Jabbour SK, DeLaney TF, Mahmoud O. Utilization pattern and survival outcomes of adjuvant therapies in high-grade non-retroperitoneal abdominal soft tissue sarcoma; a population based study. Asia Pac J Clin Oncol. doi: 10.1111/ajco.12683.

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