Children with B-cell acute lymphoblastic leukemia (B-ALL) who were positive for CD200 and/or CD56 expression had significantly poorer overall survival (OS) and disease-free survival (DFS), according to findings from a small study.
Investigators noted that CD200 expression was not significantly associated with age, sex, male gender, splenomegaly, or lower hemoglobin, but was significantly associated with lower platelet count.
Aref S, Azmy E, El-bakry K, et al. Prognostic impact of CD200 and CD56 expression in pediatric B-cell acute lymphoblastic leukemia patients [published online November 16, 2017. Pediatr Hematol Oncol. doi: 10.1080/08880018.2017.1363836.
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