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Frontline Pembrolizumab Improves Survival in NSCLC Patients With High PD-L1 Expression

Jason M. Broderick
Published: Thursday, Jun 16, 2016

Roger M. Perlmutter, MD, PhD

Roger M. Perlmutter, MD, PhD

Frontline pembrolizumab (Keytruda) improved overall survival (OS) versus chemotherapy in non–small cell lung cancer (NSCLC) patients with high levels of PD-L1 expression, according to results from the phase III KEYNOTE-024 trial reported by Merck, the company developing the PD-1 inhibitor.

 
Garon EB, Rizvi N, Hu R, et al. Pembrolizumab for the treatment of non–small cell lung cancer. N Engl J Med. 2015;372:2018-2028.

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