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Genetic Model Predicts Age of Onset for Aggressive Prostate Cancer

Jason Harris
Published: Friday, Jan 19, 2018

Prostate Cancer

Tyler M. Seibert, MD, PhD
By combining data from genome-wide association studies (GWAS) with epidemiological surveys, investigators say they have developed a genetic tool that can predict age of onset for aggressive prostate cancer.

= .14). The score remained predictive when adjusted for family history.
Seibert TM, Fan CC, Wang Y, et al. Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts [published online January 10, 2018]. BMJ doi: 10.1136/bmj.j5757.

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