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Genomic, Transcriptomic Profiling Lays Groundwork for Personalization in RCC

Caroline Seymour
Published: Tuesday, Jan 29, 2019

A. Ari Hakimi, MD

A. Ari Hakimi, MD

RNA-based analyses of prospectively-collected tumor specimens from patients with metastatic renal cell carcinoma (mRCC) in the phase III COMPARZ trial revealed 4 molecular subgroups, of which a high angiogenesis expression and a low macrophage infiltrate were indicative of response to frontline TKI therapy.1

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