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Improving CAR T-Cell Therapies With Greater Understanding of Cancer Immunology

Caroline Seymour
Published: Tuesday, Oct 08, 2019

Eduardo Sotomayor, MD, professor of medicine, Department of Hematology and Oncology, and director, GW Cancer Center

Eduardo Sotomayor, MD

The two FDA approved CD19-directed CAR T-cell constructs—axicabtagene ciloleucel (axi-cel; Yescarta) and tisagenlecleucel (Kymriah)—have revolutionized the field of oncology, and provided a foundation to create additional constructs to overcome resistance mechanisms and minimize treatment-related toxicity, said Eduardo Sotomayor, MD.
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