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Multimodality Approach Best for CNS Disease in NSCLC

Brandon Scalea
Published: Monday, Feb 18, 2019

Sarah B. Goldberg, MD

Sarah B. Goldberg, MD
Radiation is still a staple in the treatment of patients with lung cancer who develop central nervous system (CNS) metastases, but novel targeted therapies are also showing promising CNS activity, said Sarah B. Goldberg, MD, MPH.

, Goldberg shed light on the complex treatment paradigm for patients with lung cancer who have CNS metastases and highlighted emerging treatment strategies for those with mesothelioma.

OncLive: What are the current approaches for managing CNS disease in patients with oncogene-driven lung cancer?

Goldberg: Brain metastases are, unfortunately, very common for patients with lung cancer in general; this is probably even more true for patients with oncogene-driven tumors—specifically those with EGFR and ALK abnormalities. There are several options available for patients with brain metastases.
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