News >

Nivolumab Spurs Responses in non-CRC Patients With dMMR

Anita T. Shaffer @Shaffer1
Published: Saturday, Nov 11, 2017

Dr Nilofer S. Azad

Nilofer S. Azad, M
Nivolumab (Opdivo) demonstrated a 24% overall response rate (ORR) among patients with a range of non-colorectal cancers (CRCs) with mismatch repair deficiency (dMMR) who were identified through the NCI-MATCH trial, according to preliminary clinical trial findings reported at the 32nd SITC Annual Meeting.

Overall, 8 of 34 patients achieved a response for a 24% ORR (95% CI, 11%-41%); all were deemed partial responses (PRs) although there were 2 unconfirmed complete responses. “We did meet our primary endpoint,” Azad said. “…Of note, we had 5 more patients who had unconfirmed responses. Two of those patients remained on study at the time of data cutoff, so these response numbers may change as the study matures.”
... to read the full story
To Read the Full Story

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Medical Crossfire®: How Can We Optimize Outcomes in Head and Neck Cancers with Immunotherapeutic Strategies?Oct 31, 20191.5
The Patient and Provider Connection™: Effective Communication to Optimize the Diagnosis and Management of Irritable Bowel Syndrome and Chronic Idiopathic ConstipationOct 31, 20191.0
Publication Bottom Border
Border Publication
x