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No Benefit Observed From Combined Irradiation in Intermediate-Risk Prostate Cancer

Published: Thursday, Oct 06, 2016

Bradley R. Prestidge, MD

Bradley R. Prestidge, MD

The addition of external-beam radiotherapy (EBRT) to interstitial brachytherapy failed to reduce prostate cancer progression compared to brachytherapy alone in men with intermediate-risk disease, interim data from a randomized trial showed.1,2

Follow-up will continue until the data reach a cutoff for efficacy or futility, Bradley R. Prestidge, MD, a radiation oncologist at Bon Secours Cancer Institute and DePaul Medical Center, reported at the 2016 American Society for Radiation Oncology (ASTRO) Annual Meeting in Boston, Massachusetts.

“Among men with intermediate-risk prostate cancer, the addition of external-beam therapy to brachytherapy did not result in superior freedom from progression compared with brachytherapy alone at 5 years in this initial report,” Prestidge concluded. “Toxicity in both groups was limited, but there were fewer late effects, mostly genitourinary, noted in the brachytherapy-alone arm.”
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