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Older CRC Patients at Increased Risk for New-Onset Cardiotoxicity

Jason Harris
Published: Tuesday, Jan 23, 2018

Kelly M. Kenzik, PhD

Kelly M. Kenzik, PhD
Older patients with colorectal cancer (CRC) are more likely to develop cardiovascular disease (CVD) and congestive heart failure (CHF), according to results from an analysis of the SEER database. Researchers reported that both diabetes and hypertension interact with chemotherapy to increase the cardiovascular risk for these patients.

<.001). All preexisting comorbidities, with the exception of liver disease, significantly accelerated time to CVD.
Kenzik KM, Balentine C, Richman J, et al. New-onset cardiovascular morbidity in older adults with stage I to III colorectal cancer [published online January 16, 2018]. J Clin Oncol doi: 1200/JCO.2017.74.97

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