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PD-L1 Expression Strongly Associated With Radiation Resistance in HPV-Negative HNSCC

Jason Harris
Published: Thursday, May 11, 2017

Heath D. Skinner, MD, PhD

Heath D. Skinner, MD, PhD

High PD-L1 expression was closely associated with local failure following radiotherapy in HPV-negative head and neck squamous cell carcinomas (HNSCC), according to results recently published online in Clinical Cancer Research.

“Immuno-oncology has taken the field by storm. I think there is an enormous role for radiation to play in that field.”
Skinner HD, Giri U, Yang LP, et al. Integrative analysis identifies a novel AXL–PI3 kinase–PD-L1 signaling axis associated with radiation resistance in head and neck cancer [published online May 11, 2017]. Clin Cancer Res. 10.1158/1078-0432.CCR-16-2586.

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Online CME Activities
TitleExpiration DateCME Credits
Medical Crossfire®: How Can We Optimize Outcomes in Head and Neck Cancers with Immunotherapeutic Strategies?Oct 31, 20191.5
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