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SF3B1 Mutation Associated With Poor Survival in CLL

Jason Harris
Published: Monday, Aug 07, 2017

Researchers in China have concluded that mutation of the SF3B1 gene is “significantly associated” with poorer progression-free survival (PFS) and overall survival (OS) in patients with chronic lymphocytic leukemia (CLL).

Sensitivity analysis suggested that no individual study significantly affected the pooled hazard ratios.
Zhang Z, Chen S, Chen S, et al. SF3B1 mutation is a prognostic factor in chronic lymphocytic leukemia: a meta-analysis [published online July 22, 2017]. Oncotarget. doi:10.18632/oncotarget.19455.

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