The Current Standard-of-Care for Patients with HER2+ Metastatic Breast Cancer
October 6th 2022Neil M. Iyengar, MD briefly reviews the standard-of-care first-line treatment for patients with metastatic HER2+ breast cancer as well as historical approaches to progression after first-line treatment.
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Patient Profile 1: Sequencing Therapies in HER2+ mBC
April 15th 2022Shared insights on the use of therapies as a patient progresses with HER2+ metastatic breast cancer, which includes sequencing through T-DM1 [trastuzumab emtansine], tucatinib/capecitabine/trastuzumab, and trastuzumab deruxtecan.
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Treatment Advances in HR+/HER2- MBC
Final takeaways from a discussion on best practices treating HR+/HER2- metastatic breast cancer with CDK4/6 inhibitors and PI3K therapies based on data presented at ESMO 2021.
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Managing Patients With HR+ MBC on PI3K Therapy
Breast oncologists share pearls regarding best practices treating patients with HR+/HER2- metastatic breast cancer with PI3K inhibitor therapy and mitigating treatment-related adverse events.
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PI3K Inhibitors for PIK3CA-Mutated HR+ MBC
Considerations for treating patients with HR+/HER2- metastatic breast cancer with alpelisib, a PI3K inhibitor, following frontline treatment with a CDK4/6 inhibitor.
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CDK4/6 Treatment Selection for HR+/HER2- MBC
The impact of recent data presented at ESMO 2021 in terms of selecting an appropriate CDK4/6 inhibitor as first-line treatment of HR+/HER2- metastatic breast cancer.
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HR+/HER2- MBC: CKD4/6 Inhibitor Treatment Toxicities
Clinical pearls regarding best practices preventing and/or managing common treatment-related adverse events associated with CDK4/6 inhibitors used to treat HR+/HER2- metastatic breast cancer.
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MONALEESA Data in HR+/HER2- MBC: Sequencing Therapy
Insight on how to best sequence therapy for patients with HR+/HER2- advanced breast cancer based on updated data from the MONALEESA trials.
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Ribociclib + ET for HR+/HER2- MBC: QoL and OS Data
Considerations regarding the association of quality of life with overall survival in patients with HR+/HER2- advanced breast cancer treated with ribociclib and endocrine therapy.
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Frontline Treatment Approaches for HR+/HER2- MBC
A panel of breast oncologists review first-line treatment options for patients with HR+/HER2- metastatic breast cancer, commenting on treatment advances utilizing CKD4/6 inhibitors.
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HR+ MBC: Prognostic Factors and Treatment Planning
Dr. Neil Iyengar highlights variables that factor into treatment decisions for patients with HR+/HER2- metastatic breast cancer.
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