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Sumanta Kumar Pal, MD, FASCO, discusses key biomarker analyses in renal cell carcinoma that will be presented at the 2024 ASCO Annual Meeting.

Dr Pal Previews ASCO 2024 Data in Renal Cell Carcinoma

Most women who attempted to conceive following treatment for stage I to III breast cancer were able to become pregnant at least once.

Prospective Data Reveal Most Young Survivors of Breast Cancer Could Successfully Give Birth

Patients under the age of 40 who received HPV vaccines were associated with lower rates of HPV-related cancer vs unvaccinated patients.

HPV Vaccinations Associated With Lower Rates of HPV-Caused Cancers in Patients Under 40 Years of Age

An artificial intelligence-based navigation tool may be used to call patients who previously missed their colonoscopy appointment with the goal that they will reschedule and attend the new appointment. 

AI Virtual Navigation May Reengage Patients to Undergo Missed Colonoscopies 

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Sanjal Desai, MD, discusses the feasibility of venetoclax rechallenge following progression on BTK inhibitors in chronic lymphocytic leukemia. 

Desai Details Efforts Exploring Treatment Strategies in CLL Post–BTK Inhibitor Progression

Sarah ES Leary, MD, MS, details the significance of the FDA-approval of tovorafenib for patients with relapsed or refractory BRAF-positive pediatric low-grade glioma. 

Tovorafenib Offers an Efficacious Option for R/R BRAF-Positive Pediatric Low-Grade Glioma 

James Knight, MD, discusses a case study of a patient with brain metastases from prostate cancer and the importance of multidisciplinary, comprehensive care.   

Broadening Differentials in Brain-Metastatic Prostate Cancer Broadens Diagnostic Horizons

Sameer Patel, MD, FACS, of Fox Chase Cancer Center, was recently named Vice President of the Robert H. Ivy Society of Plastic Surgeons. 

Fox Chase Cancer Center’s Dr. Sameer Patel Named Vice President of the Robert H. Ivy Society of Plastic Surgeons

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Post-Conference Perspectives: Recent Advances in the Management of Chronic GvHD

Videos

Preet M. Chaudhary, MD, PhD and Noah Merin, MD, PhD discuss the chronic graft versus host disease treatment landscape, covering first- and second-line treatments and emergent trial data.

Preet M. Chaudhary, MD, PhD and Noah Merin, MD, PhD review how chronic GvHD is diagnosed, the different types of chronic GvHD, and key risk factors for the disease.

The Chronic GvHD Landscape:  Risk Factors and Diagnosis 

Expert clinicians discuss first-line treatment methodologies for chronic GvHD, with a focus on tailoring treatments to the patient. 


First-line Treatment for Patients with Chronic GvHD

Dr. Merin defines steroid refractory chronic GvHD, explains how to determine when patients become steroid-refractory and discusses treatment approach for this population. 


Defining and Managing Steroid Refractory Chronic GvHD

Dr. Chaudhary introduces data supporting the use of ruxolitinib as a first-line option in patients with steroid-refractory chronic GvHD. 


Role of Ruxolitinib in Steroid-Refractory Chronic GvHD

Dr. Merin describes the mechanisms of action of ruxolitinib, ibrutinib, and belumosudil and shares clinical pearls for community oncologists on methods for achieving response with these agents.

Understanding Mechanisms of Action: Ruxolitinib, Ibrutinib, and Belumosudil

A brief review of the key efficacy data for two treatment options, Ibrutinib and Belumosudil, in patients with chronic GvHD.

Key Efficacy Data of Ibrutinib and Belumosudil in Steroid-Refractory Chronic GvHD Patients

Discussion centered around real-world data following the approval of ruxolitinib as a treatment option for patients with chronic GvHD as well as discussing  treatment selection for patients with chronic GvHD, with special consideration for treatment sequencing.

Real World Data on the Use of Ruxolitinib and Treatment Selection in chronic GvHD

Dr. Chaudhary and Dr. Merin discuss potential areas for exploration and unmet needs in the chronic GvHD treatment landscape. 

Future Directions in Chronic GvHD

Defining and Managing Steroid Refractory Chronic GvHD

EP: 1.The Chronic GvHD Landscape: Risk Factors and Diagnosis

EP: 2.First-line Treatment for Patients with Chronic GvHD

EP: 3.Defining and Managing Steroid Refractory Chronic GvHD

EP: 4.Role of Ruxolitinib in Steroid-Refractory Chronic GvHD

EP: 5.Understanding Mechanisms of Action: Ruxolitinib, Ibrutinib, and Belumosudil

EP: 6.Key Efficacy Data of Ibrutinib and Belumosudil in Steroid-Refractory Chronic GvHD Patients

EP: 7.Real World Data on the Use of Ruxolitinib and Treatment Selection in chronic GvHD

EP: 8.Future Directions in Chronic GvHD

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