One of the major developments in cancer treatment in recent years has been the potential of drugs that target the oncogenic PI3K/Akt pathway and mTOR, a downstream effector of the pathway.
Pharmaceutical industry analysts and companies have been weighing in on their selections for the most noteworthy research to be presented during the 2012 ASCO Annual Meeting.
Axitinib joins three other multi-tyrosine kinase inhibitors, two mTOR inhibitors, and an antiangiogenic therapy as available treatments for metastatic RCC.