Dr. Cortes Discusses FLT3 Inhibitors in AML

J​orge E. Cortes, MD
Published: Thursday, Jun 22, 2017



Jorge E. Cortes, MD, professor and deputy chair, Department of Leukemia, The University of Texas MD Anderson Cancer Center, discusses FLT3 Inhibitors in acute myeloid leukemia (AML).

Cortes says that one of the most common mutations in AML is FLT3-internal tandem duplication (ITD). Until recently, there has not been much progress in developing agents for this population.

FLT3 inhibitors under development are quizartinib, crenolanib, and gilteritinib. There have been some good responses with these inhibitors as single agents, says Cortes, but they tend to be transient.
 


Jorge E. Cortes, MD, professor and deputy chair, Department of Leukemia, The University of Texas MD Anderson Cancer Center, discusses FLT3 Inhibitors in acute myeloid leukemia (AML).

Cortes says that one of the most common mutations in AML is FLT3-internal tandem duplication (ITD). Until recently, there has not been much progress in developing agents for this population.

FLT3 inhibitors under development are quizartinib, crenolanib, and gilteritinib. There have been some good responses with these inhibitors as single agents, says Cortes, but they tend to be transient.
 

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Oncology Best Practice™: Choosing Therapies for Patients with EGFR-Mutant Lung Cancers: More Options... More Decisions... Better OutcomesFeb 28, 20182.0
Clinical Vignette Series: 34th Annual Chemotherapy Foundation Symposium: Innovative Cancer Therapy for Tomorrow®Feb 28, 20182.0
Publication Bottom Border
Border Publication
x