An Explorer's Mentality Leads to Novel Treatments in Prostate and Bladder Cancer
December 10th 2018Although he held a longtime fascination with space exploration to the moon and Mars, Daniel P. Petrylak, MD, took a different path and broke new ground in another frontier: genitourinary oncology.
New Strategies Are Needed as Ovarian Cancer Becomes a Chronic Disease
December 10th 2018Since the introduction of platinum agents in ovarian cancer, it is reasonable to suggest there have been only limited changes in the basic paradigm of ovarian cancer management over the past several decades.
Robust Future Ahead for Stem Cell Transplants
December 6th 2018Although many new drugs have been introduced for treating patients with hematologic malignancies, stem cell transplantation remains a vital part of the therapeutic paradigm, particularly for multiple myeloma and non-Hodgkin lymphoma.
Investigators Seek Expanded Use of Checkpoint Inhibitors in RCC
December 5th 2018In contrast to the wide array of available therapies in the metastatic setting of renal cell carcinoma, in patients with localized disease, the results of trials investigating adjuvant systemic therapy after nephrectomy have so far been underwhelming.
Novel Antibody-Drug Conjugate Enters Phase III Trial for Metastatic TNBC
December 4th 2018Investigators are optimistic about sacituzumab govitecan (IMMU-132), an antibody–drug conjugate that delivers the chemotherapy metabolite SN-38 to tumor cells expressing the TROP-2 receptor, for patients with relapsed/refractory TNBC.