Oncologists Prepare to Bridge Knowledge Gap on Clinical Trial Outcomes With Patients
May 8th 2023When patients with cancer are asked to be participants in a clinical trial, they are informed that a primary purpose of the investigative effort is to develop objectively valid, generalizable information that may be of value to patients with the same malignancy or benefit researchers in the development of future studies.
Kim Discusses the Development of LP-300 Plus Chemotherapy in Advanced Lung Cancer
April 27th 2023Dr Kim discusses the evaluation of LP-300 for the treatment of patients with advanced lung adenocarcinoma, the rationale for exploring this agent in combination with chemotherapy, and the ongoing HARMONIC trial investigating the combination of LP-300 plus carboplatin and pemetrexed.
Taking Organoids From Bench to Bedside Through Endoscopy in Pancreatic Cancer: Ongoing Research
April 27th 2023In this seventh episode of OncChats: Taking Organoids From Bench to Bedside Through Endoscopy in Pancreatic Cancer, Toufic A. Kachaamy, MD, Madappa Kundranda, MD, PhD, and Richard Burkhart, MD, discuss ongoing research such as the PASS-01 trial (NCT04469556) in pancreatic cancer and ways to translate advances in the metastatic setting to the curative setting.
BASECAMP-1 Aims to Identify Patients Eligible for Treatment With Novel CAR T-Cell Agent
Looking to replicate the impressive findings with CAR T-cell therapies observed in patients with hematologic malignancies, investigators have initiated the BASECAMP-1 trial, with the hope of identifying patients with advanced solid tumors who will be suitable candidates for treatment in a subsequent trial evaluating the investigational agent A2B530.
Hemostatic Radiotherapy Represents Tool for Management of GI Bleeding in Advanced Cancer
Hemostatic radiation is a method of managing bleeding in patients with gastrointestinal cancers or GI metastases from other primary tumors; however, a multidisciplinary team is required to implement this method, according to Marnee M. Spierer, MD, MBA.
Taking Organoids From Bench to Bedside Through Endoscopy in Pancreatic Cancer: Organoid Collection
April 13th 2023In this third episode of OncChats: Taking Organoids From Bench to Bedside Through Endoscopy in Pancreatic Cancer, Toufic A. Kachaamy, MD, Madappa Kundranda, MD, PhD, and Richard Burkhart, MD, highlight the three ways in which an organoid can be used to aid clinical sequencing and treatment selection in pancreatic cancer.
Novel CDK9 Inhibitor Under Investigation in Solid Tumors and NHL
April 5th 2023Miguel Villalona-Calero, MD, discusses the unique mechanism of action of KB-0742 and the rationale and design of a phase 1 trial investigating the safety and efficacy of KB-0742 in patients with relapsed/refractory solid tumors or non-Hodgkin lymphoma.
Understanding Endoscopy in the Realm of GI Cancers: An Evolving Field
April 5th 2023In this seventh episode of OncChats: Understanding Endoscopy in the Realm of GI Cancers, Madappa Kundranda, MD, PhD, and Toufic A. Kachaamy, MD, discuss the convergence of gastroenterology and interventional gastroenterology in gastrointestinal cancer management and the future of interventional endoscopy.
Understanding Endoscopy in the Realm of GI Cancers: Efforts to Advance the Field
March 31st 2023In this sixth episode of OncChats: Understanding Endoscopy in the Realm of GI Cancers, Madappa Kundranda, MD, PhD, and Toufic A. Kachaamy, MD, share efforts to increase awareness around endoscopy in gastrointestinal cancer.
Understanding Endoscopy in the Realm of GI Cancers: Endoscopic Oncology and Existing Barriers
March 29th 2023In this fifth episode of OncChats: Understanding Endoscopy in the Realm of GI Cancers, Madappa Kundranda, MD, PhD, and Toufic A. Kachaamy, MD, review the potential role for endoscopic ablation in gastrointestinal cancer.
Understanding Endoscopy in the Realm of GI Cancers: Endoscopic Cancer Resection
March 24th 2023In this fourth episode of OncChats: Understanding Endoscopy in the Realm of GI Cancers, Madappa Kundranda, MD, PhD, and Toufic A. Kachaamy, MD, provide insight on the use of endoscopic submucosal resection and endoscopic evaluation for tumor response as it pertains to organ preservation in gastrointestinal cancer.
Understanding Endoscopy in the Realm of GI Cancers: Examining the Role of Endoscopy
March 22nd 2023In this third episode of OncChats: Understanding Endoscopy in the Realm of GI Cancers, Madappa Kundranda, MD, PhD, and Toufic A. Kachaamy, MD, highlight the advantages and scope of endoscopic procedures in gastrointestinal cancer.
Understanding Endoscopy in the Realm of GI Cancers: Interventional Oncology
March 17th 2023In this second episode of OncChats: Understanding Endoscopy in the Realm of GI Cancers, Madappa Kundranda, MD, PhD, and Toufic A. Kachaamy, MD, explain the evolution of minimally invasive surgery and the emergence of interventional radiology in gastrointestinal cancer.
Understanding Endoscopy in the Realm of GI Cancers: Multidisciplinary Care
March 15th 2023In this first episode of OncChats: Understanding Endoscopy in the Realm of GI Cancers, Madappa Kundranda, MD, PhD, and Toufic A. Kachaamy, MD, discuss the importance of endoscopic oncology as it relates to rising cancer incidence and multidisciplinary care in gastrointestinal cancer.
Dr. Dorff on the Continued Investigation of Upfront Chemotherapy in mHSPC
March 10th 2023Tanya Dorff, MD, discusses key data supporting the use of intensified triplet regimens in metastatic hormone-sensitive prostate cancer, and remaining questions regarding the role of chemotherapy agents in these combinations.